Diabetes & Cancer a lethal combination
An article was published in Diabetologia, which revealed that patient having a pre-existing diabetes had a greater risk of death and this was highest when observed in those using insulin. This was a Danish study which found that patients who had diabetes for 2 years, and who had been treated with insulin at the time of cancer diagnosis, had a mortality rate that was about 4 times higher than that of non diabetics. Among 426129 patients with cancer, 42205 patients were having diabetes prior to their cancer diagnosis. Diabetic had a poor survival as compared to non diabetic and this difference was more marked when compared to diabetics on insulin.
Various co-morbidities associated with diabetes may be one of the reasons but there may be a “direct effect” from glucose lowering regimens that induce a “more progressive cancer at diagnosis &/or impaired prognosis". Although author emphasise that the study is entirely observational so no definitive conclusion can be drawn and only trends are observed and hypothesis is generated for future studies.
An article was published in Diabetologia, which revealed that patient having a pre-existing diabetes had a greater risk of death and this was highest when observed in those using insulin. This was a Danish study which found that patients who had diabetes for 2 years, and who had been treated with insulin at the time of cancer diagnosis, had a mortality rate that was about 4 times higher than that of non diabetics. Among 426129 patients with cancer, 42205 patients were having diabetes prior to their cancer diagnosis. Diabetic had a poor survival as compared to non diabetic and this difference was more marked when compared to diabetics on insulin.
Various co-morbidities associated with diabetes may be one of the reasons but there may be a “direct effect” from glucose lowering regimens that induce a “more progressive cancer at diagnosis &/or impaired prognosis". Although author emphasise that the study is entirely observational so no definitive conclusion can be drawn and only trends are observed and hypothesis is generated for future studies.
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